It seems only yesterday that the self-proclaimed Rap God was beefing with Machine Gun Kelly after shots were made on his much-praised 10th studio album, Kamikaze, but it appears Em has landed himself in hot water with another music star after mocking Ariana Grande and the Manchester bombing in his 11-minute freestyle, 'Kick Off'.
The video, which was uploaded on social media by the star this week, saw Eminem take aim at many current pop acts and movie stars, including Christina Aguilera, Justin Bieber, Snoop Dogg, and Reese Witherspoon.
Of course, the name that sparked the most outrage was Ariana Grande's, whose attendance at the Manchester Arena bombing was much-publicized.
The Grande lines read, "Like an Islamic regime, a jihadist extreme radical / Suicide bomber that's seeing / Ariana Grande sing her last song of the evening.
"And as the audience from the damn concert is leaving / Detonates the device strapped to his abdominal region / I'm not gonna finish that for obvious reasons."
The reference to the May 2017 attack, which saw Ariana Grande play to a sold-out crowd before a bomb detonated in the foyer left 22 people dead and hundreds injured.
In an open letter to her fans after the terrorist attack, Grande wrote, "The spirit of the people of Manchester, the families affected by this horrendous tragedy, and my fans around the world have permanently impacted all of us for the rest of our lives.
"Their love, strength, and unity showed me, my team, my dancers, band, and entire crew not to be defeated. To continue during the scariest and saddest of times. To not let hate win. But instead, love as loudly as possible, and to appreciate every moment."
But Grande wasn't Em's only lyrical victim. He also namedropped Justin Bieber, comparing him to a good Catholic boy-turned-bad. "Justin Beiber in a Catholic school/ selling dust and reefer while your back is to him."
The 11-minute freestyle was uploaded to Marshall Mather's Twitter account this week. It was accompanied by a caption that outlines his intentions to return to face-to-face rap battles. "The release of BODIED has me feeling nostalgic about battle rap so I headed down to my old stomping grounds."
As for the Grande issue, there's still no response from her or her family. But one person who was on the end of Grande's wrath was the British news anchor Piers Morgan, who didn't take too kindly to Morgan's comments regarding the nudity in a photo shoot form the girl group Little Mix, which he said was an overt way of using their bodies to sell records.